报告题目：Combining targeted AP-MS with phosphoproteome analysis maps the TOR/SnRK1 signaling pathway in plants.

报告人：Geert De Jaeger 教授 (比利时根特大学VIB研究所)

    Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium.

    VIB-UGent Center for Plant Systems Biology, Technologiepark 927, 9052 Gent, Belgium.

报告时间：2019年9月20日下午2:30 – 4:00 

报告地点：资环楼B211

报告人简介：

De Jaeger is full professor in Plant Biotechnology at Ghent University where he teaches Molecular Genetics and Gene Technology of plants. Besides he is Group leader/Associate Science director at the VIB-UGent Center for Plant Systems Biology where he leads a research group entitled Functional Interactomics.

De Jaeger’s technology driven research team obtained high visibility in the plant research field with their state of the art AP-MS platform that maps protein interaction networks in plants. His main research interest is the molecular regulation of plant growth at both the cellular and organ level in arabidopsis and corn to discover new strategies for the engineering of crop yield. He recently started the exploration of nutrient signaling in relation to growth, with the aim to contribute towards a more sustainable agriculture.

He currently authored 90 A1 publications with more than 4000 life time citations, a H-index of 38, and he published 7 patents.

5 publications that are representative of his scientific career:

1.Van Leene J., Han C., Gadeyne A., Eeckhout D., Matthijs C., Cannoot B., De Winne N., Persiau G., Van De Slijke E., Van de Cotte B., Stes E., Van Bel M., Storme V., Impens F., Gevaert K., Vandepoele K., De Smet I. and De Jaeger G. (2019) Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Nature Plants 5, 316–327.

2.Nelissen H., Eeckhout D., Demuynck K., Persiau G., Walton A., Van Bel M., Vervoort M., Candaele J., De Block J., Aesaert S., Van Lijsebettens M., Goormachtig S., Vandepoele K., Van Leene J., Muszynski M., Gevaert K., Inzé D. and De Jaeger G. (2015). Dynamic changes in ANGUSTIFOLIA3 complex composition reveal a growth regulatory mechanism in the maize leaf. Plant Cell 27, 1605-1019.

3.Gadeyne A., Sánchez-Rodríguez C., Vanneste S., Di Rubbo S., Zauber H., Vanneste K., Van Leene J., De Winne N., Eeckhout D., Persiau G., Van De Slijke E., Cannoot B., Vercruysse L., Mayers J.R., Adamowski M., Kania U., Ehrlich M., Schweighofer A., Ketelaar T., Maere S., Bednarek S.Y., Friml J., Gevaert K., Witters E., Russinova E., Persson S., De Jaeger G. and Van Damme D. (2014). The TPLATE adaptor complex drives clathrin-mediated endocytosis in plants. Cell 156, 691-704.

4.Van Leene J., Hollunder J., Eeckhout D., Persiau G., Van De Slijke E., Stals H., Van Isterdael G., Verkest A., Neirynck S., Buffel Y., De Bodt S., Maere S., Laukens K., Pharazyn A., Ferreira P.C.G., Eloy N., Renne C., Meyer C., Faure J.-D., Steinbrenner J., Beynon J., Larkin J.C., Van de Peer Y., Hilson P., Kuiper M., De Veylder L., Van Onckelen H., Inzé D., Witters E. and De Jaeger G. (2010). Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Mol. Syst. Biol. 6, 397.1-397.12.

5.Van Leene J., Stals H., Eeckhout D., Persiau G., Van De Slijke E., Van Isterdael G., De Clercq A., Bonnet E., Laukens K., Remmerie N., Henderickx K., De Vijlder T., Abdelkrim A., Pharazyn A., Van Onckelen H., Inzé D., Witters E. and De Jaeger G. (2007). A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana. Mol. Cell. Proteomics 6, 1226-1238.