姓名:王秀娥
性别:女
毕业院校:南京农业大学
最高学位:博士
办公地址:理科楼A210
电子邮箱:xiuew@njau.edu.cn
研究方向:
麦类遗传育种;分子细胞遗传学;基因组学;抗病遗传育种。面向小麦育种对重要性状新基因特别是抗病新基因资源的迫切需求,致力于麦类作物新基因的发掘、鉴定、定位、克隆和育种利用以及种质创新的方法和技术研究,主要内容包括:1)分子细胞遗传学和基因组学与小麦种质创新;2)小麦及近缘物种重要育种目标性状基因发掘、定位、克隆和作用机制解析;3)小麦染色体工程和分子育种。
个人简介:
本科(1987年)毕业于北京农业大学农学专业,硕士研究生(1993年)和博士研究生(1996年)毕业于南京农业大学作物遗传育种专业。1987-1990年在河北省农林科学院谷子研究所工作;1997年至今在南京农业大学工作至今。1999~2000年美国堪萨斯州立大学访问学者,2004~2005年美国威斯康辛大学博士后。现任南京农业大学教授、农学院副院长、作物遗传与种质创新国家重点实验室常务副主任、农业部华东地区作物基因资源与种质创制重点实验室主任,江苏省遗传学会理事长,中国遗传学会、中国作物学会、中国农业与生物技术学会、植物生理与分子生物学会女科学家分会理事,作物学报、农业生物技术学报、Plant Growth Regulation等编委。先后主持国家自然基金等项目30余项;获国家科技进步二等奖 (8/40)和国家技术发明二等奖(排名2/6)各1项,教育部高校科学研究优秀成果奖(技术发明奖和科技进步奖)一等奖各1项(排名2/6,5/6);发表论文160余篇,其中SCI论文60余篇。参编教材和专著4部。获批发明专利15项,参加育成小麦新品种2个,获批植物新品种保护权2项。
科研项目(在研):
2017.1-2020.12兼抗两种以上小麦真菌病害的抗性位点发掘、定位及种质创新,国家自然科学基金国际(地区)合作与交流项目,200万元
2017.6-2018.6江苏现代农业(小麦)产业技术体系遗传育种创新团队,江苏省农业三新工程,30万元
2016.1~2020.12农业科研杰出人才及其创新团队,100万元
2016.7-2020.12重要基因组区段的遗传效应分析,创制小麦与野生近缘种染色体工程基础材料,国家重点研发计划,220万元
2016.7-2020.12小麦抗赤霉病和白粉病的功能基因组与调控网络,国家重点研发计划,70万元
2015.1~2018.12簇毛麦HvCMPG互作蛋白基因HvFP3在小麦抗白粉病中的功能及作用机制,国家自然科学基金。100万元
2015.8-2018.6以赤霉病防控为核心技术的小麦区域化高产安全技术方案,江苏省农业科技自主创新基金,60万元
荣誉奖项:
1. 农业部杰出人才及创新团队,2015年
2. 南京农业大学优秀教师,2011年
3. 江苏省“333”工程第二层次,2012年和2016年
4. 江苏省六大人才高峰,2012年
5. 江苏省现代农业产业技术创新团队2013
6. 江苏省现代农业产业体系小麦遗传育种岗位科学家,2017
科研奖项:
1. “小麦-簇毛麦新种质创制与利用”,2012年国家技术发明奖二等奖(完成人排名2/6);
2. “小麦-簇毛麦新种质创制与利用”,2011年教育部技术发明奖一等奖(完成人排名2/6);
3. “小麦抗病生物技术育种研究及其应用”,2005年教育部科技进步二等奖(完成人排名8/33);
4. “小麦抗病生物技术育种研究及其应用”,2006年国家科技进步二等奖(完成人排名8/33);
5. “小麦异染色体系及近缘物种的细胞与分子遗传学研究”,1999年教育部科学技术进步一等奖(完成人排名5/11);
6. 2001年江苏省教育厅江苏省第一届优秀博士学位论文。
7. 被评为“2009-2011”南京农业大学优秀教师;
8. 参加的研究生“细胞遗传学”(刘大钧负责建设)课程2002年被评为江苏省研究生培养创新工程优秀研究生课程
发明专利:
1. 曹爱忠,陈佩度; 王秀娥; 王苏玲,张守忠, 与小麦抗白粉病基因Pm21连锁的共显性PCR标记及其用法, 中国, 中国国家专利局(授权), ZL200410103073.x.
2. 陈雅平,陈佩度; 王秀娥; 张守忠,王苏玲,周波, 一个与小麦抗白粉病基因Pm21连锁的共显性PCR标记及其用法, 中国, 中国国家专利局, ZL200510040991.7.
3. 曹爱忠; 王秀娥; 邢莉萍,王海燕,王苏玲,周波,陈佩度, 一个簇毛麦丝氨酸/苏氨酸激酶基因及其所编码的蛋白质, 中国, 中国国家专利局, ZL200610085629.6.
4. 王秀娥; 纪剑辉,曹爱忠,王海燕,陈佩度,刘大钧, 与小麦抗白粉病基因Pm6连锁的标记引物及其用法, 中国, 中国国家专利局, ZL200610088312.8.
5. 刘大钧,尚毅,马璐琳; 王秀娥; 亓增军,曹爱忠,邢莉萍,陈佩度, 一个小麦PDR型的ABC转运蛋白基因及其所编码的蛋白质, 中国, 中国国家专利局, ZL200810243901.8.
6. 刘大钧,马璐琳,尚毅; 王秀娥; 亓增军,曹爱忠,邢莉萍,陈佩度, 二磷酸尿核苷葡萄糖基转移酶基因及其所编码的蛋白质, 中国, 中国国家专利局, ZL200810022415.3.
7. 王秀娥; 曹爱忠,王慰,刘园,王海燕,陈佩度, 一个簇毛麦泛素连接酶基因及其编码的蛋白质, 中国, 中国国家专利局, 200910184505.7.
8. 王秀娥 李颖波 曹爱忠 王海燕 邢莉萍 祝燕飞 王慰 费菲一个簇毛麦二硫化物异构酶基因及其应用ZL201310041504.3
9. 贾新平 王秀娥 肖进 王海燕 曹爱忠 邢莉萍 赵维萍 李明浩 陈炜 金夏红 裴海岩一个小麦非特异性脂转移蛋白基因及其所编码的蛋白质和应用ZL201210296704.9
10. 王海燕,赵仁慧,陈忠明,肖进,曹爱忠,贾琪,袁春霞,王秀娥。抗小麦黄花叶病毒的簇毛麦4VS染色体的特异分子标记。专利号:201310172525.9,发文日:2014年8月25日,发文序号:2014082000078030
11. 邢莉萍,曹爱忠,胡佳梦,李颖波,王秀娥,陈佩度.一个簇毛麦钙调素互作蛋白激酶基因及其表达载体和应用. ZL201210512583.7,授权公告日2015.06.03
12. 邢莉萍,曹爱忠,钱晨,王秀娥,陈佩度.一种高效基因枪转化小麦叶片单细胞瞬间表达的方法及其应用. ZL201210507031.7授权公告日2015.03.11
13. 李颖波,王秀娥,曹爱忠,王海燕,邢莉萍,肖进,费菲,祝燕飞。一个簇毛麦金属转运蛋白基因及其所编码的蛋白质和应用。ZL201210574738.X 授权公告日2015/2/25
14. 王秀娥,程江月,李颖波,肖进,王宗宽,王海燕,曹爱忠,邢莉萍,祝燕飞,Muhammad Faheem,袁春霞,郝永利,赵佳,陈炜,陈忠明 。一个簇毛麦凝集素类受体激酶基因及其表达载体和应用。201510101972.7
15. 曹爱忠,葛帅,刑书娟,邢莉萍,蒋正宁,张国琴,王秀娥,陈佩度. 一个具F-BOX结构域的基因TaFBK1及其表达载体和应用.申请号:201510016489.6 (2015)
16. 曹爱忠,钱晨,李若晨,邢莉萍,胡平,周渭皓,王慧,王秀娥,陈佩度. 小麦中一个NAC转录因子基因TaNACs及其表达载体和应用. 申请号:201510045191.8(2015)
代表性论(译)著:
著作:
1. 刘大钧; 吴兰佩; 陈佩度; 齐莉莉; 王秀娥; 曹明树, 细胞遗传学, 中国农业出版社, 1999/5.
2. 马鸿翔,王秀娥,程顺和,王海燕等。《中国南方小麦》,江苏科学技术出版社,2012
3. Haiyan Wang, Zhengui Liu, Peidu Chen; *Xiue Wang, FAO/IAEA Plant Mutation Breeding and Biotechnology Textbook :: C19, FAO/IAEA Plant Mutation Breeding and Biotechnology Textbook, Qingyao Shu, IAEA, pp 223-240, Joint FAO/IAEA Division, International Atomic Energy Agency, Austria, BP Forster, BioHybrids International Limited, UK, H Nakagawa, Biomass Research & Development Center National Agriculture and Food Research Organization (NARO), Japan, 2012, Hardback, 978178064085-编著
4. 张红生,鲍永美,胡白石,王秀娥等。《植物抗病虫育种》,科学出版社,2012,译著
5. 曹墨菊,王秀娥等。《植物生物技术概论》,中国农业大学出版社,2014,编著
论文:
1. Zongkuan Wang, Jiangyue Cheng, Anqi Fan, Jia Zhao, Zhongyu Yu, Yingbo Li, Heng Zhang, Jin Xiao, Faheem Muhammad, Haiyan Wang, Aizhong Cao, Liping Xing, Xiue Wang*. LecRK-V, an L-type lectin receptor kinase in Haynaldia villosa, plays positive role in resistance to wheat powdery mildew. Plant Biotechnology Journal. 2018, online first.
2. JIA Haojie Sun, Jingjing Song, Jin Xiao, Tao Xu, Xing Wei, Chunxia Yuan, Aizhong Cao, Liping Xing, Haiyan Wang* and Xiue Wang* Development of EST-PCR Markers Specific to the Long Arm of Chromosome 6V of Dasypyrum villosum. JIA, 2018 online first
3. Jin Xiao, Xueluan Chen, Zhitian Xu, Jiao Guo, Zhenzhen Wu, Haiyan Wang, Xiaobiao Zhu, Mingjuan Nie,Tongde Bie, Shunhe Cheng, TingTing Zhu, Mingcheng Luo, Frank M. You, Xiue Wang. Validation and diagnostic marker development for a genetic region associated with wheat yellow mosaic virus resistance. Euphytica (2017) 211:91–101.DOI 10.1007/s10681-016-1731-1
4. Jin Xiao, Manoj Kumar Sekhwal, Pingchuan Li, Raja Ragupathy, Sylvie Cloutier, Xiue Wang and Frank M. You. Pseudogenes and Their Genome-Wide Prediction in Plants. International Journal of Molecular Sciences. 2017
5. Tao Xu, Nengfei Bian, Mingxing Wen, Jin Xiao, Chunxia Yuan, Aizhong Cao, Shouzhong Zhang, Xiue Wang*, Haiyan Wang*. Characterization of a common wheat (Triticum aestivum L.) high‑tillering dwarf mutant. Theor Appl Genet, 2017, 130:483–494
6. Haiyan Wang1, Keli Dai1, Jin Xiao1, Chunxia Yuan1, Renhui Zhao1, Jaroslav Doležel2, Yufeng Wu1, Aizhong Cao1, Peidu Chen1, Shouzhong Zhang1, Xiue Wang Development of Intron Targeting (It) Markers Specific for Chromosome Arm 4vs of Haynaldia Villosa by Chromosome Sorting and Next-Generation Sequencing, BMC Genomics,2017-09-06
7. Tingting Chen, Jin Xiao, Jun Xu, Wentao Wan, Bi Qin, Aizhong Cao, Wei Chen, Liping Xing, Chen Du, Xiquan Gao Shouzhong Zhang Ruiqi Zhang Wenbiao Shen Haiyan Wang and Xiue Wang, Two members of TaRLK family confer powdery mildew resistance in common wheat. BMC Plant Biology (2016) 16:27
8. Yuxin Sun,Jin Xiao,Xinping Jia,Peibei Ke,Liqiang He,Aizhong Cao,Haiyan Wang,Yufeng Wu,Xiquan Gao,Xiue Wang.The role of wheat jasmonic acid and ethylene pathways in response to Fusarium graminearum infection. Plant Growth Regulation, September 2016, Volume 80, Issue 1. 69–77
9. Muhammad Faheem , Yingbo Li, Muhammad Arshad, Cheng Jiangyue, Zhao Jia, Zongkuan Wang, Jin Xiao, Haiyan Wang, Aizhong Cao, Liping Xing, Feifei Yu, Ruiqi Zhang, Qi Xie & Xiue Wang, A disulphide isomerase gene (PDI-V) from Haynaldia villosa contributes to powdery mildew resistance in common wheat. Sci Rep. 2016; 6: 24227.Published online 2016 April 13. doi: 10.1038/srep24227
10. Yuan Fang, Ximeng Wang, Lei Wang, Xiucai Pan, Jin Xiao, Xiu-e Wang, Yufeng Wu & Wenli Zhang, Functional characterization of open chromatin in bidirectional promoters of rice. Scientific Reports 2016, 6, Article number: 32088 doi:10.1038/srep32088
11. Yuan Fang,Lei Wang,Ximeng Wang,Qi You,Xiucai Pan,Jin Xiao,Xiu-e Wang,Yufeng Wu,Zhen Su,Wenli ZhangEmail author. Histone modifications facilitate the coexpression of bidirectional promoters in rice. BMC Genomics (2016) 17: 768. doi:10.1186/s12864-016-3125-0
12. Yanfei Zhu, Yingbo Li, Fei Fei, Zongkuan Wang, Wei Wang, Aizhong Cao, Yuan Liu, Shuang Han, Liping Xing, Haiyan Wang, Wei Chen, Sanyuan Tang, Xiahe Huang, Qianhua Shen, Qi Xie,* and Xiue Wang,* E3 ubiquitin ligase gene CMPG1–V from aynaldia villosa L. contributes to powdery mildew resistance in common wheat (Triticum aestivum L.)。The Plant Journal (2015) 84, 154–168
13. Wei Chen, Qilin Zhu, Haiyan Wang, Jin Xiao, Liping Xing, Peidu Chen, Weiwei Jin, Xiu-E. Wang*. Competitive Expression of Endogenous Wheat CENH3 May Lead to Suppression of Alien ZmCENH3 in Transgenic Wheat 3 Maize Hybrids。Journal of Genetics and Genomics 42 (2015) 639-649
14. Manoj Kumar Sekhwal , Pingchuan Li, Irene Lam, Xiue Wang, Sylvie Cloutier and Frank M. You*. Disease Resistance Gene Analogs (RGAs) in Plants. International Journal of Molecular Sciences. 2015, 16, 19248-19290
15. Yuan Lu, Liping Xing, Shujuan Xing, Ping Hu, Chaofan Cui, Mingyi Zhang, Jin Xiao, Haiyan Wang, Ruiqi Zhang, Xiue Wang, Peidu Chen, Aizhong Cao. Characterization of a Putative New Semi-Dominant Reduced Height Gene, Rht_NM9, in Wheat (Triticum aestivum L.)》Journal of Genetics and Genomics, 2015, 42:685-698
16. Shulin Chen, Runhong Gao, Haiyan Wang, Mingxing Wen, Jin Xiao, Nengfei Bian, Ruiqi Zhang, Wenjing Hu, Shunhe Cheng, Tongde Bie, Xiue Wang (corresponding author), Characterization of a novel reduced height gene (Rht23) regulating panicle morphology and plant architecturein bread wheat. Euphytica, 2015, 203:583–594
17. Yuhui Fang, Jingya Yuan, Zhangjun Wang, Haiyan Wang, Jin Xiao, Zhixi Yang,Ruiqi Zhang, Zengjun Qia, Weigang Xu, Lin Hu, Xiu-E Wang (corresponding author), Development of T. aestivum L.eH. californicum Alien Chromosome Lines and Assignment of Homoeologous Groups of Hordeum californicum Chromosomes. Journal of Genetics and Genomics, 2014, 41:439-447
18. Zhang Ruiqi, Zhang Mingyi, Wang Xiue, Chen Peidu, Introduction of chromosome segment carrying the seed storage protein genes from chromosome 1V of Dasypyrum villosum showed positive effect on bread‑making quality of common wheat. Theor Appl Genet, 2014, 127:523–533
19. Liping Xing, Chen Qian, Aizhong Cao, Yingbo Li, Zhengning Jiang, Minghao Li, Xiahong Jin, Jiameng Hu, Yiping Zhang, Xiue Wang (corresponding author), Peidu Chen* , The Hv-SGT1 Gene from Haynaldia villosa Contributes to esistances Towards Both Biotrophic and Hemi-Biotrophic Pathogens in Common Wheat (Triticum estivum L.). PLOS ONE, 2013, 8(9): e72571
20. Renhui Zhao, Haiyan Wang, Jin Xiao, Tongde Bie, Shunhe Cheng, Qi Jia, Chunxia Yuan, Ruiqi Zhang, Aizhong Cao, Peidu Chen, Xiue Wang(corresponding author), Induction of 4VS chromosome recombinants using the CS ph1b mutant and mapping of the wheat yellow mosaic virus resistance gene from Haynaldia villosa. Theor Appl Genet, 2013, 126: 2921-2930
21. Jiang, Zhengning; Ge, Shuai; Xing, Liping; Han, Dejun; Kang, Zhensheng; Zhang, Guoqin; Wang, Xiaojie; Wang, Xiue; Chen, Peidu*; Cao, Aizhong*, RLP1.1, a novel wheat receptor-like protein gene, is involved in the defence response against Puccinia striiformis f. sp tritici, Journal of Experimental Botany, 2013, 64(12): 3735-3746
22. Ma, Hongbo, Zhang, Xiao, Wang, Canguo, Gao, Derong, Zhang, Boqiao, Lv, Guofeng, Wu, Ronglin, Cheng, Xiaoming, Wang, Xiue, Cheng, Shunhe*; Bie, Tongde*, Effect of wx genes on amylose content, physicochemical properties of wheat starch, and the suitability of waxy genotype for producing Chinese crisp sticks, Journal of Cereal Science, 2013, 58(1):140-147
23. Xiao J, Jin XH, Jia XP, Wang HY, Cao AZ, Zhao WP, Pei HY, Xue ZK, He LQ, Chen QG, Wang XE (corresponding author). Transcriptome-based discovery of pathways and genes related to resistance against Fusariumhead blight in wheat landrace Wangshuibai. BMC Genomics, 2013, 14:197
24. Peidu Chen, Chunfang You, Yin Hu, Shengwei Chen, Bo Zhou, Aizhong Cao, Xiue Wang. Radiation-induced translocations with reduced Haynaldia villosa chromatin at the Pm21 locus for powdery mildew resistance in wheat. Mol Breeding, 2013, 31:477-484
25. Yuefeng Shen, Jian Shen, Dawadondup, Lifang Zhuang,Yanzhi Wang, Jing Pu, Yigao Feng, Chenggen Chu, Xiue Wang, Zengjun Qi. Physical localization of a novel blue-grained gene derived from Thinopyrum bessarabicum. Mol Breeding, 2013, 31:195–204
26. Bi Qin, Tingting Chen, Aizhong Cao, Haiyan Wang, Liping Xing, Hongqing Ling, Daowen Wang, Chunmei Yu, Jin Xiao, Jianhui Ji, Xueluan Chen, Peidu Chen, Dajun Liu, Xiue Wang (corresponding author). Cloning of a conserved receptor-like protein kinase gene and its use as a functional marker for homoeologous group-2 chromosomes of the Triticeae species. PLOS ONE, 2012, 12(7):1-12
27. Xiaobiao Zhu, Haiyan Wang, Jiao Guo, Zhenzhen Wu, Aizhong Cao, Tongde Bie, Mingjuan Nie, Frank M. You, Zhaobang Cheng, Jin Xiao, Yangyang Liu, Shunhe Cheng, Peidu Chen, Xiue Wang (corresponding author). Mapping and validation of quantitative trait loci associated with wheat yellow mosaic bymovirus resistance in bread wheat. Theor Appl Genet. 2012, 124:177–188
28. Zhang, RQ; Wang, XE; Chen, PD. Molecular and cytogenetic characterization of a small alien-segment translocation line carrying the softness genes of Haynaldia villosa. Genome, 2012, 55:1-8
29. Cao, AZ, Xing, LP, Wang, XY , Yang, XM, Wang, W, Sun, YL, Qian, C, Ni, JL, Chen, YP , Liu, DJ , Wang, X (corresponding author), Chen, PD*. Serine/threonine kinase gene Stpk-V, a key member of powdery mildew resistance gene Pm21, confers powdery mildew resistance in wheat. Proceedings of the National Academy of Sciences of the United States of America. 2011,108 (19): 7727-7732
30. Haifeng Li, Bikram S. Gill, Xiue Wang, Peidu Chen. A Tal-PhI wheat genetic stock facilitates efficient alien introgression. Genetic Resources and Crop Evolution. 2011, 58( 5): 667-678
31. Jin Xiao, Xinping Jia, Haiyan Wang, Renhui Zhao, Yuhui Fang, Runhong Gao, Zhenzhen Wu, Aizhong Cao, Jia Wang, Zhaokun Xue, Weiping Zhao, Jixiong Kang, QiGuang Chen, Peidu Chen, Xiue Wang (corresponding author). A Fast-neutron Induced chromosome Fragment Deletion of 3BS in wheat landrace Wangshuibai Increased Its Susceptibility to Fusarium Head Blight. Chromosome Research. 2011, 19(2):225-234
32. Bi Qin, Aizhong Cao, Haiyan Wang, Tingting Chen, Frank M. You, Yangyang Liu, Jianhui Ji, Dajun Liu, Peidu Chen and Xiu-e Wang (corresponding author). Collinearity-based marker mining for the fine mapping of Pm6, a powdery mildew resistance gene in wheat. Theoretical and Applied Genetics.2011,123 (2): 207-218
33. Yi Shang, Lulin Ma, Haiyan Wang, Wei Feng, Peidu Chen, Xuying Cao, Dajun Liu, Xiu-e Wang (corresponding author). The evolutionary history of PDR in Brachypodium distachyon polyploids. Mol Biol Rep. 2011, 38: 2211–2217
34. Lulin Ma, Yi Shang, Aizhong Cao, Zengjun Qi, Liping Xing, Peidu Chen, Dajun Liu, Xiu-e Wang (corresponding author), Molecular cloning and characterization of an up-regulated UDP-glucosyltransferase gene induced by DON from Triticum aestivum L. cv. Wangshuibai. Mol Biol Rep. 2010, 37:785-795
35. Ruiqi Zhang, Yaping Cao, Xiue Wang, Yigao Feng and Peidu Chen, Development and characterization of a Triticum aestivum-H. villosa T5VS·5DL translocation line with soft grain texture. Journal of Cereal Science,2010, 51(2): 220-225
36. Yi Shang, Jin Xiao, Lulin Ma, Haiyan Wang, Zengjun Qi, Peidu Chen, Dajun Liu, Xiu-e Wang (corresponding author), Characterization of a PDR type ABC transporter gene from wheat (Triticum aestivum L.). Chinese Sci Bull, 2009, 54 (17): 2500-2507
37. Wang Xiaoyun, Chao Aizhong, Yu Chunmei, Wang Daowen, Wang Xiue, Chen Peidu. Establishment of an effective virus induced gene silencing system with BSMV in Haynaldia villosa. Mol Biol Rep. 2010, 37: 967-972
38. Wenli Zhang, Xiue Wang(Co-First author), Qingyi Yu, Ray Ming, and Jiming Jiang, DNA methylation and heterochromatinization in the male-specific region of the primitive Y chromosome of papaya. Genome Research.2008, 18: 1938-1943
39. Ji Jianhui, Qin Bi, Wang Haiyan, Cao Aizhong, Wang Suling, Chen Peidu, Zhuang Lifang, Du Yu, Liu Dajun, Wang Xiue(correspondence author). STS markers for powdery mildew resistance gene Pm6 in wheat. Euphytica, 2008, 163:159-165
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