余玲
发布时间:2012-09-10 浏览次数:
 

余玲

一、 简历:

1,2004 年获得以色列希伯来大学(Hebrew University of Jerusalem)植物生物 学博士学位;

2, 2004-2012 年在美国埃默里大学 (Emory University) 医学院从事动物细胞离 子稳态平衡机制研究(2004-2009 博士后,2009-2012 聘为 Research Faculty), 2012-2015 聘为 Adjunct Professor。

3, 2012 年至今,南京农业大学资环学院教授、博士生导师。

二、 研究领域: 1, 植物营养分子生物学 2, 植物 耐盐分子育种

三、 主持科研项目:

1,2013 年 1 月 - 2016 年 12 月,国家自然基金委面上项目(80 万):耐盐菊芋 两个钠 (钾)氢逆向转运蛋白调控钾钠平衡和耐盐力差异的作用机制。

2, 2013 年 1 月 - 2015 年 12 月,教育部博士点基金 (12 万):水稻高亲和钾转 运体 OsHAK1 的功能研究。

3,2013 年 10 月 - 2016 年 9 月, 国家自然科学基金委 国际(地区)重大合作项 目(200 万):一石二鸟 - 揭秘高亲和钾转运体调控水稻株型的机理。

4,2013 年 1 月 - 2015 年 12 月,植物营养生物学江苏省创新团队骨干成员(共 300 万, 本人获得 100 万的支助)。

5,2014-2016 年,转基因新品种培育重大专项,参与子课题(本人可支配 70 万):磷钾高效关键基因及其调控元件的功能及其育种价值鉴定。

6, 2016 年 1 月-2020 年 12 月,转基因生物新品种培育重大专项的子课题,主持 (2016-2018 年已划拨 78 万)。

7,2016 年 7 月-2020 年 12 月,国家重点研发计划:主要农作物养分高效利用性 状形成的遗传与分子基础,水稻钾高效子课题主持(本人获得资助 130 万)。

四、 发表文章:

1, Rice potassium transporter OsHAK1 is essential for maintaining potassium mediated growth and functions in salt tolerance over low and high potassium concentration ranges. Plant Cell and Environment. 2015. 38(12):2747-65.

 2, Improving rice tolerance to potassium deficiency by enhancing OsHAK16p:WOX11-controlled root development. Plant Biotechnol J. 2015. 13(6):833-48.

3, The role of OsHAK5 in potassium acquisition and transport from roots to shoots in rice at low potassium supply levels. Plant Physiology. 2014. 166 (2), 945–959.

4, Do phosphoinositides regulate membrane water permeability of tobacco protoplasts by enhancing the aquaporin pathway? Planta. 2015. 241(3):741- 55.

5, Functional analyses of a putative plasma membrane Na+/H+ antiporter gene isolated from salt tolerant Helianthus tuberosus. Mol Biol Rep. 2014. 41(8):5097-108.

6, Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity. PLoS One. 2016. 11(11):e0165763.

7, The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate. Biochem J. 2016. 473(19):3237-52.

8, The Polarized Effect of Intracellular Calcium on the Renal Epithelial Sodium Channel Occurs as a Result of Subcellular Calcium Signaling Domains Maintained by Mitochondria. J Biol Chem. 2015. 290(48):28805-11.

9, Unoprostone activation of BK (KCa1.1) channel splice variants. Biochim Biophys Acta. 2015. 1848(11 Pt A):2859-67.

10, Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane. Am J Physiol Renal Physiol. 2015. 309(5):F456-63.

11, Basolateral P2Xchannels stimulate ENaC activity in Xenopus cortical collecting duct A6 cells. Am J Physiol Renal Physiol. 2014. 307(7):F806-13.

12, Cytochalasin E alters the cytoskeleton and decreases ENaC activity in Xenopus 2F3 cells. Am J Physiol Renal Physiol. 2014. 307(1):F86-95.

13, WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination. Am J Physiol Renal Physiol. 2013. 305(1):F31-41.

14, The inhibitory effect of Gâã and Gâ isoform specificity on ENaC activityAm J Physiol Renal Physiol. 2013. 305(9): F1365–F1373.

15, Estradiol activates epithelial sodium channels in rat alveolar cells through the G protein-coupled estrogen receptor. Am J Physiol Lung Cell Mol Physiol. 2013. 305(11):L878-89.

16, Phosphatidylinositol phosphate-dependent regulation of Xenopus ENaC by MARCKS protein. Am J Physiol Renal Physiol. 2012. 303(6):F800-11.

17, β-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo. Am J Physiol Lung Cell Mol Physiol. 2012. 302(11):L1167-78.

18, Regulation of epithelial sodium channel trafficking by ubiquitination. Proc Am Thorac Soc. 2010. 7(1):54-64.

19, Two rice phosphate transporters, OsPht1;2 and OsPht1;6, have different functions and kinetic properties in uptake and translocation. Plant J. 2009. 57(5):798-809.

20, Phosphatidylinositol (4,5)bisphosphate inhibits K+-efflux channel activity in NT1 tobacco cultured cells. Plant Physiol. 2009. 149(2):1127-40.

21, Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells. Am J Physiol Renal Physiol. 2008. 295(5):F1519-27. 22, Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells. Am J Physiol Renal Physiol. 2007. 293(5):F1666-77.

23, Effect of divalent heavy metals on epithelial Na+ channels in A6 cells. Am J Physiol Renal Physiol. 2007. 293(1):F236-44.

24, Phosphorylation of SPICK2, an AKT2 channel homologue from Samanea motor cells. J Exp Bot. 2006. 57(14):3583-94.

25, Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia. Am J Physiol Cell Physiol. 2005. 289(3):C717-26.

26, Extracellular protons inhibit the activity of inward-rectifying potassium channels in the motor cells of Samanea saman pulvini. Plant Physiol. 2001. 127(3):1310-22.